How Can Cortisone Travel Through The Epidermis?

How Can Cortisone Travel Through The Epidermis? Cortisone must be lipid soluble so it can easily diffuse through the cell membrane. Cortisone is a steroid that is applied to the skin to reduce inflammation. Cortisone acts on cells within the dermis and can travel through unbroken epidermis to reach cells in the dermis. Which epidermal