Does The Urea Cycle Only Happen In The Liver?

Does The Urea Cycle Only Happen In The Liver? NAG=N-acetylglutamate, an allosteric activator of carbamoyl phosphate synthetase. Liver is the only organ that contains the complete urea cycle and is the major site of ureagenesis. Where does the urea cycle occur? The urea cycle or ornithine cycle converts excess ammonia into urea in the mitochondria