viral polymerases

What Viruses Use RNA Dependent RNA Polymerase?

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What Viruses Use RNA Dependent RNA Polymerase? The best-known RdRps are polioviral 3Dpol, vesicular stomatitis virus L, and hepatitis C virus NS5B protein. Many eukaryotes also have RdRps and these are involved in RNA interference: these amplify microRNAs and small temporal RNAs and produce double-stranded RNA using small interfering RNAs as primers. Does influenza have

Why Do RNA Viruses Have High Mutation Rates?

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Why Do RNA Viruses Have High Mutation Rates? The RNA polymerase that copies the virus’s genes generally lacks proofreading skills, which makes RNA viruses prone to high mutation rates—up to a million times greater than the DNA-containing cells of their hosts. Why are RNA mutation rates so high? The high mutation rate of RNA viruses