The chondrocytes in the growth plates are surrounded by matrix consisting of proteoglycan aggregates and are divided into three zones,
reserve/resting zone, proliferative zone and hypertrophic zone
.
What are the five zones in the epiphyseal plate?
resting zone, 2. proliferation zone, 3. hypertrophic cartilage zone, 4
. calcified cartilage zone
, and 5.
What are the 4 zones of the epiphyseal plate?
- Proliferation Zone. Zone 1. Cartilage cells undergo mitosis.
- Hypertrophic Zone. Zone 2. Older cartilage cells enlarge.
- Calcification Zone. Zone 3. Matrix becomes calcified; cartilage cells die; matrix begins deteriorating.
- Ossification Zone. Zone 4. New bone formation is occurring.
What are the zones in the epiphyseal plate quizlet?
- Name all of the zones of the epiphyseal plate. Resting cartilage, proliferation, hypertrophy, calcification, ossification.
- function of the epiphyseal plate. …
- Zone of resting cartilage. …
- Zone of Proliferation. …
- Zone of hypertrophy. …
- hypertrophy. …
- Zone of calcification. …
- Zone of ossification.
What is the correct order of zones in the epiphyseal plate?
The topmost layer of the epiphysis
is the reserve zone
. The second zone, the proliferative zone, is where chondrocytes are continually undergoing mitosis. The next zone is the zone of maturation and hypertrophy where lipids, glycogen, and alkaline phosphatase accumulate, causing the cartilaginous matrix to calcify.
Is the zone of resting cartilage?
Zone of reserve
(“resting”) cartilage (unmodified hyaline). 2. Zone of proliferating cartilage . . . clusters (cell nests) of chondrocytes undergo successive mitotic divisions to form columns of cells separated by deeply staining matrix.
How the epiphyseal plate grows?
Bones grow in length at the epiphyseal plate by a process that is
similar to endochondral ossification
. The cartilage in the region of the epiphyseal plate next to the epiphysis continues to grow by mitosis. The chondrocytes, in the region next to the diaphysis, age and degenerate.
What is the epiphyseal plate?
A growth plate, also called an epiphyseal plate, is
a section of cartilage located at the ends of the long bones of children
and teenagers. It is here that new bone develops to add length as the child grows.
What happens in zone of reserve cartilage?
Zone of reserve cells: A thin layer (3-6 cells wide) of
small, randomly oriented chondrocytes adjacent
to the bony trabeculae on the articular side of the growth plate. Zone of proliferation: Chrondrocytes are stacked in prominent rows and the cartilage matrix becomes more basophilic in this zone.
What are the growth plate zones?
The chondrocytes in the growth plates are surrounded by matrix consisting of proteoglycan aggregates and are divided into three zones,
reserve/resting zone, proliferative zone and hypertrophic zone
.
What happens in the zones of the epiphyseal plate?
The epiphyseal plate is the
area of growth in a long
bone. It is a layer of hyaline cartilage where ossification occurs in immature bones. On the epiphyseal side of the epiphyseal plate, cartilage is formed. On the diaphyseal side, cartilage is ossified, allowing the diaphysis to grow in length.
What happens when the epiphyseal plate is ossified quizlet?
Chondrocyte replication and hypertrophy resulted in interstitial cartilage growth, interstitial cartilage growth increases the length of the bone, Ossification of calcified cartilage produces additional
bone
on the diaphyseal side of the epiphyseal plate, and thickness of epiphyseal plate remains unchanged because the …
What is the role of the epiphyseal plate?
The epiphyseal growth plate is
the main site of longitudinal growth of the long bones
. At this site, cartilage is formed by the proliferation and hypertrophy of cells and synthesis of the typical extracellular matrix. The formed cartilage is then calcified, degraded, and replaced by osseous tissue.
What is atavistic epiphysis?
Atavistic epiphysis:
A bone that is independent phylogenetically but is now fused with another bone
. These types of fused bones are called atavistic, e.g., the coracoid process of the scapula, which has been fused in humans, but is separate in four-legged animals.
Which zone of the epiphyseal plate consists of rapidly dividing cartilage?
Near the outer end of each epiphyseal plate
is the active zone dividing the cartilage cells. Some of them, pushed toward diaphysis with proliferative activity, develop hypertrophy, secrete an extracellular matrix, and finally the matrix begins to fill with minerals and then is quickly replaced by bone.
Which zone of the epiphyseal plate is located the farthest from the marrow space?
Cartilage to Bone
Zone of reserve cartilage
: This region is farthest from the marrow cavity and consists of hyaline cartilage that does not actively transform into bone. Quiescent chondrocytes are found here.
