:
containing or being a chemical ring that consists usually of 15 or more atoms
.
Which is smallest polyene macrocycle?
Natamycin
, the smallest macrocycle, is a pentaene; nystatin is a hexaene; and amphotericin B is a heptaene. The polyenes have no activity against bacteria, rickettsia, or viruses, but they are highly potent, broad-spectrum anti-fungal agents. They do have activity against certain protozoa, such as Leishmania spp.
What does the word macrocyclic mean?
:
containing or being a chemical ring that consists usually of 15 or more atoms
.
What does Contruded mean?
:
to understand
(an action, event, remark, etc.) in a particular way. : to understand the meaning of (a word, phrase, or sentence)
What does Sultrous mean?
1a :
very hot and humid
: sweltering a sultry day. b : burning hot : torrid a sultry sun. 2a : hot with passion or anger. b : exciting or capable of exciting strong sexual desire sultry glances.
What does polyene mean?
:
an organic compound containing many double bonds especially
: one having the double bonds in a long aliphatic hydrocarbon chain. Other Words from polyene Example Sentences Learn More About polyene.
What are the two classes of polyene antifungal?
The major targets for antifungal drugs are the cell wall and plasma membrane. The major groups of antifungals in use today are the polyene (
amphotericin B and nystatin
) and azole (e.g. voriconazole) classes which target ergosterol in the fungal plasma membrane and ergosterol synthesis, respectively [3].
What is polyene antifungal?
Polyene Antifungal Drugs
These drugs interact with sterols in cell membranes (ergosterol in fungal cells; cholesterol in human cells) to form channels through the membrane, causing the cells to become leaky (Fig. 76-2). The polyene antifungal agents include
nystatin, amphotericin B, and pimaricin
.
Could be construed as meaning?
construe sth as sth
to understand the meaning, especially of other people’s actions and statements, in a particular way: Any changes to the plan would be construed as
indecision
.
What does Congitation mean?
1a :
the act of cogitating
: meditation. b : the capacity to think or reflect. 2 : a single thought. Synonyms Example Sentences Learn More About cogitation.
What is a sultry voice?
A sultry voice sounds confident, and when the speaker laughs,
it sounds light and sexy
. Singers with sultry voices, like Betty Carter and Emily King, are said to be hypnotic and enticing.
Can a man be sultry?
The definition of sultry is
very hot and moist or creating passion
. An example of sultry is a 100 degree day with 90 percent humidity. An example of sultry is a very attractive man. Extremely hot; fiery.
What is a sultry look?
A sultry atmosphere is a thick, almost swampy feeling. And all that heavy heat can certainly get passions stirring — “a sultry look” is one that
happens to express steamy desire
. Definitions of sultry. adjective. exciting in a sensual way; attractive and suggesting hidden passion.
What is polyene chain?
A linear polyene is
a chain of conjugated carbon-carbon double bonds with an unbranched n-electron system
. ... Polyenes are distinguished from symmetrical cyanines and aromatic compounds by the fact that these other compounds have at least two resonance structures which contribute significantly to their ground state.
Do humans have ergosterol?
In human nutrition, ergosterol is
a provitamin form of vitamin D
2
; exposure to ultraviolet (UV) light causes a chemical reaction that produces vitamin D
2
.
