What Drugs Should Not Be Taken With Depakote?

by | Last updated on January 24, 2024

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What drugs should not be taken with Depakote? Some products that may interact with this drug include: certain antidepressants (such as amitriptyline, nortriptyline, phenelzine), certain antibiotics (carbapenems such as imipenem), irinotecan, mefloquine, orlistat, other for seizure (such as ethosuximide, lamotrigine, phenytoin, rufinamide, topiramate), …

Why is Depakote a hazardous drug?

DEPAKOTE can cause serious side effects, including:

Serious liver damage that can cause death, especially in children younger than 2 years old

. The risk of getting this serious liver damage is more likely to happen within the first 6 months of treatment.

Can you take gabapentin and Depakote together?

Interactions between your drugs


Using gabapentin together with divalproex sodium may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating

. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

Can you take Xanax and Depakote together?

If you are a woman of childbearing age, talk to your doctor before using divalproex sodium together with ALPRAZolam.

Combining these medications may increase the risk of harmful effects to a fetus

. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

What are the serious side effects of Depakote?

  • Nausea or vomiting that does not go away.
  • Loss of appetite.
  • Pain on the right side of your stomach (abdomen)
  • Dark urine.
  • Swelling of your face.
  • Yellowing of your skin or the whites of your eyes.

Interactions between your drugs

You may need dose adjustments or special tests in order to safely take both medications together.

Small single doses of aspirin are unlikely to cause significant effects

. However, if you take aspirin over a prolonged period of time you may need your divalproex sodium levels checked.

Depakote (divalproex) is good for long-term prevention of seizures, manic episodes in bipolar disorder, and migraines.

Lowers blood pressure

and controls heart rate. Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers.

Interactions between your drugs

In addition,

sertraline can cause seizures in susceptible patients, which may reduce the effectiveness of medications that are used to control seizures such as divalproex sodium

. Talk to your doctor if you have any questions or concerns.

Valproic Acid (Depakote)

Valproic acid is an epilepsy medication that is now

used for the treatment of panic attacks as well as other psychiatric problems

. May work better by adding it to a primary medication that is not completely effective.

Anticonvulsants are sometimes taken to treat the manic episodes associated with bipolar disorder. Depakote is sometimes prescribed when patients experience rapid cycling of mood episodes and works by

calming the hyperactivity of the brain during mania

.

valproic acid traMADol


Using valproic acid together with traMADol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating

. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

Valproic Acid (Depakote): Valproic acid is an anti-seizure medication that is used for migraine pain and

may be effective at treating other types of nerve pain

.

divalproex sodium escitalopram


Treatment with escitalopram may occasionally cause blood sodium levels to get too low

, a condition known as hyponatremia, and using it with some anticonvulsants can increase that risk.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.

Some products that may interact with this drug include: certain antidepressants (such as amitriptyline, nortriptyline, phenelzine), certain antibiotics (carbapenems such as imipenem), irinotecan, mefloquine, orlistat, other medications for seizure (such as ethosuximide, lamotrigine, phenytoin, rufinamide, topiramate), …

In addition, older adults may have certain health conditions that affect how their bodies respond to Depakote and Depakote ER. These include dementia (problems with thinking, memory, and communication),

kidney problems

, and liver problems. These conditions could raise their risk of side effects from the drug.

Divalproex sodium

should be taken with food

, so take your doses with a snack or just after you have had a meal. If you have been given delayed or extended release tablets, swallow them whole with a drink of water. Do not chew or crush the tablets because they have a special protective coating.


Lithium and quetiapine

top the lists for all three phases of the illness: mania, depression, and the maintenance phase. Lurasidone and lamotrigine are either untested (lurasidone) or ineffective (lamotrigine) in mania, but they are essential tools for bipolar depression.

I agree that almost any seizure drug can cause “brain fog” but some are much worse than others. My worst was Dilantin, but

Depakote was pretty bad too

.

James Park
Author
James Park
Dr. James Park is a medical doctor and health expert with a focus on disease prevention and wellness. He has written several publications on nutrition and fitness, and has been featured in various health magazines. Dr. Park's evidence-based approach to health will help you make informed decisions about your well-being.