Downstream genes
are switched on or off at various times and in different tissues
by transcription factors (q.v.) encoded by upstream regulatory genes. A master controlling gene like eyeless (q.v.) will activate some downstream genes that encode their own transcription factors.
What is a downstream gene variant?
downstream gene variant.
A sequence variant located 3′ of a gene
. SO_0001632. 0.6. TF binding site variant.
What is upstream or downstream in DNA?
Upstream is
toward the 5′ end of the
RNA particle and downstream is toward the 3′ end. At the point when considering twofold stranded DNA, upstream is toward the 5′ end of the coding strand for the quality being referred to and downstream is toward the 3′ end.
What is downstream expression?
1 : in the same direction along a molecule of DNA or RNA as that in which transcription and translation take place and toward the end having a hydroxyl group attached to the position labeled 3′ in the terminal nucleotide a nucleotide sequence located downstream from the regulatory gene effects on the expression of …
Is downstream positive or negative?
Horizontal traps opening upstream (negative rheotaxis) were colonized by more individuals than the traps opening downstream (
positive rheotaxis
), demonstrating the great importance of movements directed downstream as a primary source of colonization of new areas.
How do you know if a gene is upstream or downstream?
Upstream is toward the 5′ end of the RNA molecule and downstream is toward the 3′ end
. When considering double-stranded DNA, upstream is toward the 5′ end of the coding strand for the gene in question and downstream is toward the 3′ end.
Is negative upstream or downstream?
Positions of the nucleotides of the upstream DNA are stated with
negative numbers
starting from the transcription initiation site while positions of the nucleotides of the downstream DNA are stated with positive numbers starting from the transcription initiation site.
What does downstream mean in biology?
Downstream. 1. (Science: molecular biology)
portions of dna or rna that are more remote from the initiation sites and that will therefore be translated or transcribed later
. 2. Shorthand term for things that happen at a late stage in a sequence of reactions.
What is downstream analysis?
Downstream analysis means
any analysis done after some common step
(the data/information flows “downstream” from the initial step). Normally this would be whatever is done after alignment, so it’s too broad of a question to give a specific answer to.
Is promoter upstream or downstream?
A promoter is a region of DNA that generally is located
upstream of a gene
and facilitates and regulates its transcription.
What are downstream effects?
relating to or happening at a later stage in a process
. downstream effects/costs. Synonyms and related words. Late or too late.
What do you mean by downstream cost?
Upstream prices are the prices paid by producers (as opposed to consumers), and are directly related to the cost of production. In contrast, downstream prices are
the prices paid by consumers at the retail level
.
What does downstream mean on modem?
Downstream channels, or “
download speed
,” refers to the data that your computer receives from the Internet. When you use your computer to download music, podcasts, games, apps, pictures or other web content, you are using your computer’s downstream bandwidth.
What direction is downstream?
Downstream means
towards where the flow ends, at the opposite end of the waterway from the source
. If you are boating from Kingston to Toronto, for example, you are heading upstream. If you are going from Kingston to Cornwall, you are travelling downstream.
What is downstream signaling?
These are terms regarding Signal Transduction, in which a series of events result in the transfer of a signal. Upstream and downstream are
used to distinguish which event happens when in relation to each other
. SO something that’s downstream of Enzyme A, happens after the activation of that enzyme.
What is upstream and downstream flow?
Upstream means that the object is going opposite to the flow of the river
. In this case you have to subtract the speed of the given object in still water from the speed of flow of the stream. Downstream means that the object is flowing along the river and in this case you have to add the speed.
