What Is A Study Endpoint?

by | Last updated on January 24, 2024

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Listen to pronunciation. (END-poynt) In clinical trials,

an event or outcome that can be measured objectively to determine whether the intervention being studied is beneficial

. The endpoints of a clinical trial are usually included in the study objectives.

What is the difference between outcome and endpoint?

The term outcome usually refers to the measured variable (eg, peak volume of oxygen or PROMIS Fatigue score), whereas an endpoint refers to the

analyzed parameter

(eg, change from baseline at 6 weeks in mean PROMIS Fatigue score).

What is a primary study endpoint?

Listen to pronunciation. (PRY-mayr-ee END-poynt)

The main result that is measured at the end of a study to see if a given treatment worked

(e.g., the number of deaths or the difference in survival between the treatment group and the control group).

What is a safety endpoint in a study?

Endpoints are measures intended to reflect the effects (efficacy endpoints) or safety (safety endpoints) of a

drug

or device.

What do you mean by endpoint?

1 :

a point marking the completion of a process or stage of a process

especially : a point in a titration at which a definite effect (such as a color change) is observed.

What is difference between primary and secondary endpoint?

The primary endpoint of a clinical trial is the endpoint for which the trial is powered. Secondary endpoints are

additional endpoints

, preferably also pre-specified, for which the trial may not be powered.

What is a primary endpoint example?

A primary endpoint is

the main measurement a trial is trying to assess

. It answers the most important question in the trial. For example: In a weight loss study: What is the average weight loss after six months?

What is a safety endpoint?

Endpoints are

measures intended to reflect the effects

(efficacy endpoints) or safety (safety endpoints) of a drug or device.

What is a measurable endpoint?

To keep it simple, an endpoint is

a measurable outcome used to determine whether the drug under investigation is beneficial

. Drug companies when their new drug isn’t more effective than placebo. (

What is a therapeutic endpoint?

What are therapeutic & clinical endpoints and why are they important in drug development? A clinical and therapeutic endpoint refers

to the occurrence of an outcome (that is, a sign or a symptom) that constitutes one of the targets of the trial

.

What is an endpoint in math?

more …

Any of the two furthest points on a line segment

. (Or generally any of the furthest points on anything.) See: Line Segment.

What is a digital endpoint?

Digital endpoints are

the newest type of endpoint

. They are assessed using data captured by a sensor, typically outside of the clinic during activities of daily living. The sensor could be worn, like an accelerometer in a smartwatch used to capture motion data.

What are endpoints in statistics?

An endpoint is

a trial outcome value that is measured for each subject

, for example, objective tumour response (OR) or time to death (overall survival or OS).

What is an example of an endpoint?

An endpoint is any device that is physically an end point on a network.

Laptops, desktops, mobile phones, tablets, servers, and virtual environments

can all be considered endpoints. When one considers a traditional home antivirus, the desktop, laptop, or smartphone that antivirus is installed on is the endpoint.

What is another name for endpoint?


finish


tape

finishing line


finishing post

How do you find the endpoint?

Given the starting point, A , and the midpoint, B , draw the line segment that connects the two. Draw a line going farther from B away from A to God-knows-where. Measure the distance from A to B and mark the same distance from B going the other way.

The point you marked is the endpoint you

seek.

Charlene Dyck
Author
Charlene Dyck
Charlene is a software developer and technology expert with a degree in computer science. She has worked for major tech companies and has a keen understanding of how computers and electronics work. Sarah is also an advocate for digital privacy and security.