Aminophylline is used to
prevent and treat wheezing, shortness of breath, and difficulty breathing caused by asthma
, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.
When is iv aminophylline used?
Aminophylline Injection is
indicated for relief of bronchospasm associated with asthma and in chronic obstructive pulmonary disease
. Maintenance therapy can be administered via larger volume infusion solutions, rate-regulated to deliver the required amount of drug each hour.
Why is aminophylline given slowly?
Intravenous Aminophylline must be administered very slowly to
prevent dangerous central nervous system and cardiovascular side-effects due to direct stimulating effect of Aminophylline
.
How does the drug aminophylline work?
Aminophylline is a bronchodilator. Aminophylline works in several ways: it
relaxes muscles in your lungs and chest to allow more air in
, decreases the sensitivity of your lungs to allergens and other substances that cause inflammation, and increases the contractions of your diaphragm to draw more air into the lungs.
When a patient is receiving aminophylline the nurse should observe for?
Patients receiving aminophylline require monitoring for
CNS effects, respiratory rate, arterial blood gasses, and serum theophylline concentrations
. Clinicians must measure serum concentrations before initiating a loading dose in a person who has taken theophylline in the last 24 hours.
What should I check before giving aminophylline?
Tell all of your health care providers and lab workers that you take aminophylline.
Have blood work checked as you have been told by the doctor
. Talk with the doctor. If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
What’s the side effects of aminophylline?
- upset stomach.
- stomach pain.
- diarrhea.
- headache.
- restlessness.
- insomnia.
- irritability.
When should I stop aminophylline infusion?
The aim is to reduce the infusion over a 10-12 hour period of time once stable. It is recommended that dose reduction begin in the morning, aiming to stop the infusion
by mid to late afternoon
.
Can aminophylline be given IV push?
Aminophylline Injection is administered by slow intravenous injection or diluted and
administered by intravenous infusion
. The solution contains no bacteriostat or antimicrobial agent and is intended for use only as a single-dose injection. When smaller doses are required the unused portion should be discarded.
How quickly does aminophylline work?
This medication may be used alone or with an inhaled bronchodilator. How fast does this medication work? This medication works
within 30 minutes
.
Which class of drug is aminophylline?
Aminophylline belongs to a group of medicines known as
bronchodilators
. Bronchodilators are medicines that relax the muscles in the bronchial tubes (air passages) of the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.
Is Aminophylline an anti inflammatory?
Aminophylline has bronchodilatory and a variety of other
anti-inflammatory properties
due to its ability to inhibit phosphodiesterase.
Does aminophylline lower blood pressure?
Aminophylline increased mean arterial pressure 12 +/- 2%, LV systolic pressure 8 +/- 1%, LV dP/dt 20 +/- 2%, velocity of myocardial fiber shortening 13 +/- 2% and heart rate 5 +/- 2%, and reduced LV end-diastolic diameter 2 +/- 0.5%.
What is the antidote for aminophylline?
Intravenous aminophylline:
morphine
as antidote to poisoning.
How do you calculate aminophylline infusion?
aminophylline into 500 ml of normal saline solution. So, 1 ml will have 1/500 × 200 = 0.5 mg of aminophylline. So, 30 mg will be present in 30/0.5 × 1 = 60 ml, which is to be administered in 1 h. So, the rate of aminophylline administration will be
16-20 drops/min
.
Does aminophylline increase heart rate?
Aminophylline competitively antagonizes the cardiac actions of adenosine at the cell surface receptors. Thus,
it increases heart rate and contractility
.
