equipoise in American English
1.
equal distribution of weight; state of balance
, or equilibrium. 2. a weight or force that balances another; counterbalance.
What is equipoise and why is it important?
Clinical equipoise, also known as the principle of equipoise,
provides the ethical basis for medical research that involves assigning patients to different treatment arms of a clinical trial
. … This applies also for off-label treatments performed before or during their required clinical trials.
What is the meaning of word equipoise?
equipoise in American English
1.
equal distribution of weight; state of balance
, or equilibrium. 2. a weight or force that balances another; counterbalance.
What is mental equipoise?
Those who do no injustice have a greater chance of maintaining their balance in the face of any wrongdoing. This is the characteristic of
a person who has attained mental quietude
. Jealousy and hatred can cause you sleepless nights. … You will degenerate mentally and spiritually if you hate anyone.
What is the principle of equipoise?
The concept of ‘equipoise’, or the ‘uncertainty principle’, has been represented as a central ethical principle, and
holds that a subject may be enrolled in a randomized controlled trial (RCT) only if there is true uncertainty about which of the trial arms is most likely to benefit the patient
.
How do you use equipoise in a sentence?
- As she stacked the cans into a pyramid, the stocker was precise in order to ensure equipoise and stop the cans from crashing down.
- Losing her equipoise seemed to always be a problem as her inner ear infection worsened without treatment.
What does equipoise mean in research?
The ethics of clinical research requires equipoise–
a state of genuine uncertainty on the part
of the clinical investigator regarding the comparative therapeutic merits of each arm in a trial.
What is equipoise according to Freedman?
Equipoise is traditionally defined as
a state of genuine uncertainty on the relative value of 2 approaches being compared in a trial
. … Freedman convincingly argued that the requirement for uncertainty on the part of each investigator (which he named theoretical equipoise) was impractical and even improbable.
Does boldenone increase testosterone?
Boldenone is an anabolic androgenic steroid and synthetic derivative of testosterone that was originally developed for veterinary use but has since become one of the more common performance-enhancing drugs that athletes test positive for in sport.
What is the difference between theoretical and clinical equipoise?
The primary difference between theoretical equipoise and clinical equipoise is that
the former requires the physician–researcher to be in a state of uncertainty during all stages of an RCT
, whereas the latter requires uncertainty within the expert clinical community.
What is the half life of equipoise?
It takes longer to withdraw from steroids with longer half-lives. The half-lives of some commonly abused steroids include: Equipoise (veterinary steroid) –
14 days
. Deca-durabolin – 14 days.
What is equipoise in motivational interviewing?
Equipoise:
The counselor’s decision to counsel with neutrality in a way that consciously avoids guiding
a client toward one particular choice or change and instead explores the available options equally.
What is Nonmaleficence in healthcare?
Nonmaleficence. Nonmaleficence is
the obligation of a physician not to harm the patient
. This simply stated principle supports several moral rules – do not kill, do not cause pain or suffering, do not incapacitate, do not cause offense, and do not deprive others of the goods of life.
What is a clinical trial study?
Clinical Trials
In a clinical trial,
participants receive specific interventions according to the research plan or protocol created by the investigators
. These interventions may be medical products, such as drugs or devices; procedures; or changes to participants’ behavior, such as diet.
Who created the Declaration of Helsinki?
The World Medical Association
has developed the Declaration of Helsinki as a statement of ethical principles to provide guidance to physicians and other participants in medical research involving human subjects.
