The antimicrobial spectrum of an antibiotic means
the range of microorganisms it can kill or inhibit
. Antibiotics can be divided into broad-spectrum antibiotics, extended-spectrum antibiotics and narrow-spectrum antibiotics based on their spectrum of activity.
What is the definition of spectrum of activity?
:
a graphic representation of a physiological reaction
specifically : physiological activity plotted against light wavelength.
What is narrow spectrum of activity?
Broad spectrum antibiotics act against a larger group of bacteria. Narrow spectrum
antibiotis target specific bacteria such as Gram positive or Gram negative
.
What is meant by narrow-spectrum antibiotics?
A narrow-spectrum antibiotic is
an antibiotic that is only able to kill or inhibit limited species of bacteria
. Examples of narrow-spectrum antibiotics include fidaxomicin and sarecycline.
What is broad and narrow-spectrum antibiotics?
Narrow-spectrum antibiotics
target a few types of bacteria
. Broad-spectrum antibiotics target many types of bacteria. Both types work well to treat infections. But using broad-spectrum antibiotics when they’re not needed can create antibiotic-resistant bacteria that are hard to treat.
What is the spectrum of activity for penicillin?
Their spectrum of activity includes that of
ampicillin
, while also encompassing Enterobacter, Providencia, Morganella, indole-positive Proteus, and Pseudomonas aeruginosa, with ticarcillin having slightly greater activity against Pseudomonas aeruginosa versus carbenicillin (19).
What are examples of narrow-spectrum antibiotics?
Examples of narrow-spectrum antibiotics are the
older penicillins (penG), the macrolides and vancomycin
. Examples of broad-spectrum antibiotics are the aminoglycosides, the 2nd and 3rd generation cephalosporins, the quinolones and some synthetic penicillins.
What is meant by narrow spectrum?
Medical Definition of narrow-spectrum
:
effective against only a limited range of organisms
narrow-spectrum antibiotics effective only against gram-negative bacteria — compare broad-spectrum.
Is Penicillin a narrow spectrum?
Penicillin V has antibiotic activity against gram-positive bacteria, but is less active against gram negative bacteria, and it is known to be one
of the narrowest spectrum antibiotics in use
.
Why do we use narrow-spectrum antibiotics whenever possible?
Narrow-spectrum antibiotics, like penicillin and amoxicillin,
target only the bacteria known to cause a specific bacterial infection
. Using these narrow-spectrum antibiotics whenever possible helps prevent the development of antibiotic resistance.
Which antibiotic is broad spectrum?
Examples of broad-spectrum antibiotics
Aminoglycosides (except for streptomycin)
Ampicillin
.
Amoxicillin/clavulanic acid (Augmentin) Azithromycin
.
What is best broad-spectrum antibiotic?
Ciprofloxacin
. Best use of this new broad-spectrum antibiotic.
Is Dysidazirine a broad-spectrum antibiotic?
Vancomycin and ofloxacin are the other important broad spectrum antibiotics. The antibiotic dysidazirine
is supposed to be toxic
towards certain strains of cancer cells.
Are broad-spectrum antibiotics good or bad?
If there’s a lot of deviation from the recommended treatment guidelines, Hyun explained, that means there’s a higher chance that patients aren’t being treated effectively. In addition, using broad-spectrum antibiotics
can put patients at higher risk of adverse events
, such as Clostridium difficile.
What are the classifications of antibiotics?
In this portal, antibiotics are classified into one of the following classes:
penicillins, fluoroquinolones, cephalosporins, macrolides
, beta-lactams with increased activity (e.g. amoxicillin-clavulanate), tetracyclines, trimethoprim-sulfamethoxazole, lincosamides (e.g. clindamycin), urinary anti-infectives, and other …
Which is not a broad-spectrum antibiotic?
Penicillin
is not a broad-spectrum antibiotic because it has a narrow spectrum and is used to treat only certain infections caused by the streptococci and staphylococci bacteria such as pneumonia.
