What Is The Hemostatic Agent In Combat Gauze?

QuikClot is a proprietary hemostatic technology consisting of a nonwoven material impregnated with kaolin, which is proven to accelerate the body’s natural clotting cascade.

What is the active ingredient in combat gauze?

The only procoagulant supplement approved by the Food and Drug Administration is Combat GauzeTM (Littlejohn, Bennett, & Drew, 2015). This product is actually the third generation of QuikClot® products in which the manufacturer replaced the zeolite with kaolin, a clay containing the active ingredient

aluminum silicate

.

What is hemostatic gauze made of?

Hemostatic wound dressings

It consists of

a smectite mineral and a superabsorbent polyacrylic polymer

that can absorb 200 times its own weight. An alternative approach to zeolite-based QuikClot®.

What is the hemostatic agent in QuikClot?

A hemostatic agent known as QuikClot, which is made from

an engineered form of the mineral zeolite

, is able to quickly stop bleeding. The engineered zeolite material contains cations (positively charged ions) that serve as cofactors in the activation of clotting proteins.

What do soldiers use to stop bleeding?

Combat Gauze

uses kaolin, a fine, white clay, to stop bleeding, Cordts said, and WoundStat granules react with blood to form a barrier, preventing more bleeding.

Where can combat gauze be used?

It is designed for

packing into deep wounds which are actively bleeding

(i.e. arterial injury in the groin). Prehospital personnel can also use combat gauze as they would any standard Kerlix gauze.

When do you use QuikClot combat gauze?

In the military and combat setting, QuikClot combat gauze is recommended as

first line treatment for life threatening hemorrhage not amenable to tourniquet placement

(Bennett and Littlejohn, 2014).

Which chemical is used to stop bleeding?

Anhydrous aluminium sulfate

is the main ingredient and acts as a vasoconstrictor in order to disable blood flow. The stick is applied directly to the bleeding site. The high ionic strength promotes flocculation of the blood, and the astringent chemical causes local vasoconstriction.

Does hemostatic gauze expire?

Z-Medica(R), LLC, a leading developer and marketer of hemostatic devices, announces today that the sterility expiration date on its QuikClot Combat Gauze(R) products including QuikClot Combat Gauze, QuikClot Combat Gauze XL, QuikClot Combat Gauze TraumaPad, and QuikClot Combat Gauze LE is

now five years

.

What is the main ingredient used in the HemCon bandage to stop bleeding?

HemCon dressing (HC) received the approval of FDA in 2003 owing to its efficacy in stopping hemorrhage. The major component is

chitosan

, which is a kind of biodegradable polysaccharide amine derived from shellfish. The positive polysaccharide amine could attract negative red blood cells to help with blood clotting.

Which is better QuikClot vs Celox?

Independent testing

⁹

on

Celox RAPID

has shown the product works on lethal injuries and significantly reduces blood loss compared to Quikclot Gauze*. As well as reducing treatment time and blood loss, a model of tactical evacuation showed that the Celox RAPID Gauze stayed in place during transport with no re-bleeding

¹⁰

.

Does the military still use QuikClot?

Two agents that were widely used by the military, QuikClot (Z-Medica, Wallingford, Connecticut) and WoundStat (TraumaCure, Bethesda, Maryland),

have been removed from the U.S. military inventory because of potential complications

, specifically thermal tissue injury to patient and provider and microemboli formation.

How do hemostatic dressings work?

Essentially, the bandage works

by becoming extremely sticky when in contact with blood

. The adhesive-like action seals the wound and controls the bleeding. The chemical makeup of the dressing, with its positive charges, attracts negatively charged red-blood cells.

What are three ways to control bleeding?

The most commonly accepted and utilized methods of hemorrhage control are

direct pressure, elevation and the use of pressure points

. All three should be used in order to attempt to control bleeding. As the amount of volume loss increases or the severity of the wound dictates, you may need to employ all three methods.

How do you stop bleeding in a field?

Apply direct pressure on the cut or wound with a clean cloth, tissue, or piece of gauze

until bleeding stops. If blood soaks through the material, don’t remove it. Put more cloth or gauze on top of it and continue to apply pressure.

How do you apply QuikClot combat gauze?

1. Apply direct firm pressure on bleeding vessel if able whilst preparing QuikClot.
2. Pack the QuikClot gauze directly into the wound at the bleeding source (wound bed or vessel).
3. Once the wound is firmly packed apply consistent pressure for at least 3 minutes or until bleeding stops.
4. Reassess for further bleeding.