Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae ; genus Flavivirus.
What type of virus is the dengue virus?
Dengue is caused by a virus of the Flaviviridae family and there are four distinct, but closely related, serotypes of the virus that cause dengue (DENV-1, DENV-2, DENV-3 and DENV-4).
What is dengue virus type 3?
Recombinant dengue virus type 3 NS1 antigen is a purified preparation of the dengue virus serotype 3 ( DENV3 ), non-structural protein 1 (NS1). DENV3 is one of four (DENV1-4) antigenically distinct, closely related viral serotypes belonging to the Flaviviridae family, genus flavivirus.
Is dengue a RNA virus?
Dengue Virus Genome and Structure
The dengue virus genome is a single strand of RNA . It is referred to as positive-sense RNA because it can be directly translated into proteins. The viral genome encodes ten genes (Figure 2). The genome is translated as a single, long polypeptide and then cut into ten proteins.
What is Type 2 dengue?
Native Dengue Virus Type 2 is a preparation of viral particles concentrated from tissue culture supernatant. Dengue Virus Type 2 is one of four antigenically distinct yet closely related viral serotypes belonging to the family Flaviviridae known to cause Dengue fever in humans.
How long will dengue last?
Symptoms of dengue typically last 2–7 days . Most people will recover after about a week.
Is dengue transmitted by kissing?
An infected mosquito can later transmit that virus to healthy people by biting them. Dengue cannot be spread directly from one person to another, and mosquitoes are necessary for transmission of the dengue virus.
Is dengue spread by touch?
Dengue cannot be spread directly from person to person . However, a person infected and suffering from dengue fever can infect other mosquitoes. Humans are known to carry the infection from one country to another or from one area to another during the stage when the virus circulates and reproduces in the blood system.
What is dengue type 4?
4 Dengue viruses are transmitted by Aedes aegypti mosquitos in epidemic and endemic outbreaks and cause acute infections.
Where is dengue most common?
The disease is common in many popular tourist destinations in the Caribbean (including Puerto Rico) , Central and South America, Southeast Asia, and the Pacific Islands. In the United States, local cases and limited spread of dengue does occur periodically in some states with hot, humid climates and Aedes mosquitoes.
Is there a vaccine for dengue?
Dengue Vaccine Globally
A vaccine to prevent dengue ( Dengvaxia® ) is licensed and available in some countries for people aged 9 to 45 years. The World Health Organization recommends that the vaccine only be given to persons with confirmed previous dengue virus infection.
How many times can you get dengue?
Dengue is caused by one of any of four related viruses: Dengue virus 1, 2, 3, and 4. For this reason, a person can be infected with a dengue virus as many as four times in his or her lifetime.
What are the warning signs of dengue?
- Abdominal pain or tenderness.
- Persistent vomiting.
- Clinical fluid accumulation.
- Mucosal bleed.
- Lethargy or restlessness.
- Liver enlargement > 2 cm.
- Laboratory finding of increasing HCT concurrent with rapid decrease in platelet count.
What is the fastest way to recover from dengue fever?
- Papaya leaf juice. Papaya leaf juice is a quite famous remedy for dengue fever. ...
- Vegetable juices. Vegetables are rich in essential nutrients. ...
- Coconut water. It is recommended to drink coconut water in dengue to avoid dehydration. ...
- Herbal tea. ...
- Neem leaves.
What is the critical stage of dengue?
The critical phase of dengue begins at defervescence and typically lasts 24–48 hours. Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue as a result of a marked increase in vascular permeability.
Does dengue need hospitalization?
Doctors say most dengue cases can be managed in the outpatient departments of hospitals and only the most severe cases need hospitalisation . The World Health Organisation or WHO has released an advisory on the symptoms in patients that should lead to hospitalisation.
