Hemophilia prevalence varies widely across the United States and is highest in
Midwestern and Northeastern states
. The estimated incidence of hemophilia among U.S. births is 1 birth per 5,617 male births for hemophilia A and 1 birth per 19,283 male births for hemophilia B.
Who is most likely to get hemophilia A?
Hemophilia A is hereditary. Because it is an X-chromosome-linked condition,
males
are more typically affected and therefore more frequently diagnosed. Hemophilia A affects 1 in 5,000 male births in the U.S., and approximately 400 babies are born with hemophilia each year.
Who is most affected by hemophilia?
Hemophilia A mostly affects
males
but females can also be affected. Approximately 1 in 5,000 newborn males have hemophilia A. Approximately 60% of individuals with hemophilia A have a severe form of the disorder. All racial and ethnic groups are equally affected by hemophilia.
What age group is most affected by hemophilia?
| Age group Percentage of people | 5-13 years 13% | 14-18 years 7% | 19-44 years 39% | Above 45 years 36% |
|---|
Are males or females more affected by hemophilia?
Males are affected more often than females
because the gene is located on the X chromosome. Hemophilia. Hemophilia is a disorder in which the blood cannot clot correctly because of a lack of a clotting factor called factor VIII.
What famous person has hemophilia?
The love of Elizabeth Taylor’s life and a Shakespearean actor for the ages,
Richard Burton
starred in 61 films and 30 plays — and was the first Hollywood star to reveal he had hemophilia. In fact, Burton and Taylor set up the Richard Burton Hemophilia Fund in 1964 to help find a cure for hemophilia.
Can hemophilia be cured?
There is currently no cure for hemophilia
. Effective treatments do exist, but they are expensive and involve lifelong injections several times per week to prevent bleeding.
Why females are not affected by haemophilia?
“Growing up, we understood that men had hemophilia and women were “carriers.” Women passed along the X-linked gene, but did not actually get hemophilia
because (it was believed) that the “good X chromosome” compensated for the X chromosome that carried hemophilia
.
What organs are affected by hemophilia?
Hemophilia can result in: Bleeding within joints that can lead to chronic joint disease and pain. Bleeding in the head and sometimes in
the brain
which can cause long term problems, such as seizures and paralysis. Death can occur if the bleeding cannot be stopped or if it occurs in a vital organ such as the brain.
At what age is hemophilia diagnosed?
In the United States, most people with hemophilia are diagnosed at a very young age. Based on CDC data, the median age at diagnosis is
36 months for people with mild hemophilia
, 8 months for those with moderate hemophilia, and 1 month for those with severe hemophilia.
Do female hemophiliacs menstruate?
Women and girls routinely put
up with heavy menstrual bleeding
, often accompanied by other tell-tale symptoms, such as bruising and prolonged bleeding after dental work or childbirth, without realising that they could have a genetic bleeding disorder.
Can a hemophiliac have a baby?
If the mother is a hemophilia carrier,
there is a chance that the baby will be born with hemophilia
. In families with a known history of hemophilia, or in those with a prenatal genetic diagnosis of hemophilia, one can plan special testing for hemophilia before the baby’s delivery.
Will the child suffer from hemophilia?
Key points about hemophilia in children
It causes an
affected child to have low levels of blood clotting factors
. The most common symptom of hemophilia is increased, uncontrollable bleeding. Giving factor VIII or IX can allow a child with hemophilia to lead a near normal lifestyle.
What is Factor 9 in the blood?
Factor IX is a protein produced naturally in the body. It
helps the blood form clots to stop bleeding
. Injections of factor IX are used to treat hemophilia B, which is sometimes called Christmas disease.
Did Queen Victoria have hemophilia?
Queen Victoria of England, who ruled from 1837-1901, is believed to have
been the carrier of hemophilia B
, or factor IX deficiency. She passed the trait on to three of her nine children. Her son Leopold died of a hemorrhage after a fall when he was 30.
How long is the average lifespan of a person with hemophilia?
During this period, it exceeded mortality in the general population by a factor of 2.69 (95% confidence interval [CI]: 2.37-3.05), and median life expectancy in severe hemophilia was
63 years
.
