As a consequence of the degeneracy of the genetic code, a point mutation will commonly result in the same amino acid being incorporated into the resulting polypeptide despite the sequence change. This change would have no effect on the protein’s structure, and is thus called
a silent mutation
.
What type of mutation has no effect on the amino acid sequence of a polypeptide multiple choice question?
As a consequence of the degeneracy of the genetic code, a point mutation will commonly result in the same amino acid being incorporated into the resulting polypeptide despite the sequence change. This change would have no effect on the protein’s structure, and is thus called
a silent mutation
.
Which type of base pair substitution mutation has no effect on the amino acid sequence of a protein quizlet?
A missense mutation
is when the change of a single base pair causes the substitution of a different amino acid in the resulting protein. This amino acid substitution may have no effect, or it may render the protein nonfunctional.
What type of substitution won’t affect the protein sequence?
A mutation that results in no protein function is called a
null mutation
. Changes that do not affect the function of a protein are called silent mutations.
What type of mutation does not change the amino acid sequence and thus has no observable consequence group of answer choices?
Silent mutations
are base substitutions that result in no change of the amino acid or amino acid functionality when the altered messenger RNA (mRNA) is translated. For example, if the codon AAA is altered to become AAG, the same amino acid – lysine – will be incorporated into the peptide chain.
What type of mutation is responsible for abnormal amino acid sequence?
Which type of mutation results in abnormal amino acid sequence?
silent mutations
.
What type of mutation does not affect a protein?
Silent mutation
: Some mutations that change DNA bases do not have any effect on the sequence of amino acids in the protein. These mutations are called silent mutations and they do not affect the structure or function of the protein because there is no effect on the amino acid sequence.
What type of mutation changes a single amino acid in a polypeptide sequence?
A missense mutation
is a mistake in the DNA which results in the wrong amino acid being incorporated into a protein because of change, that single DNA sequence change, results in a different amino acid codon which the ribosome recognizes. Changes in amino acid can be very important in the function of a protein.
What amino acid has only one codon?
Methionine is specified by the codon AUG, which is also known as the start codon. Consequently, methionine is the first amino acid to dock in the ribosome during the synthesis of proteins.
Tryptophan
is unique because it is the only amino acid specified by a single codon.
What will be the amino acid sequence?
The sequence of a protein is usually notated as a string of letters, according to the order of the amino acids from the amino-terminal to the carboxyl-terminal of the protein. Either a single or three-letter code may be used to represent each amino acid in the sequence.
What is the result of a substitution mutation?
A substitution is a mutation that exchanges one base for another (i.e., a change in a single “chemical letter” such as switching an A to a G). Such a substitution could:
change a codon to one that encodes a different amino acid and cause a small change in the protein produced
.
Do all substitutions cause a change in the amino acid sequence of a protein?
Silent substitutions never alter the amino acid sequence
of the polypeptide chain.
How does change in amino acid sequence affect protein function?
From the protein data base. Because form determines function, any slight change to a protein’s shape may cause the protein to become dysfunctional. Small changes in the amino acid sequence of a protein can cause
devastating genetic diseases
such as Huntington’s disease or sickle cell anemia.
What is an example of a missense mutation?
A missense mutation occurs when there is a mistake in the DNA code and one of the DNA base pairs is changed, for example,
A is swapped for C
. This single change means that the DNA now encodes for a different amino acid, known as a substitution.
What is the difference between missense and nonsense mutation?
Nonsense mutation:
changes an amino acid to a STOP codon
, resulting in premature termination of translation. Missense mutation: changes an amino acid to another amino acid.
What is the difference between point mutation and frameshift mutation?
Chromosomal alterations are mutations that change chromosome structure. Point mutations
change a single nucleotide
. Frameshift mutations are additions or deletions of nucleotides that cause a shift in the reading frame.
