Hemophilia prevalence varies widely across the United States and is highest in
Midwestern and Northeastern states
. The estimated incidence of hemophilia among U.S. births is 1 birth per 5,617 male births for hemophilia A and 1 birth per 19,283 male births for hemophilia B.
Where is hemophilia most common?
The two major forms of hemophilia occur much more commonly in
males
than in females. Hemophilia A is the most common type of the condition; 1 in 4,000 to 1 in 5,000 males worldwide are born with this disorder. Hemophilia B occurs in approximately 1 in 20,000 newborn males worldwide.
How common is hemophilia in the world?
The worldwide incidence of hemophilia A is
approximately 1 case per 5000 males
, with approximately one third of affected individuals not having a family history of the disorder. The prevalence of hemophilia A varies with the reporting country, with a range of 5.4-14.5 cases per 100,000 males.
How common is hemophilia in Europe?
The global incidence of haemophilia is approximately 1 per 4,000–5,000 male births; in a given year,
approximately 400 boys
are born with haemophilia in Europe [1].
Where is hemophilia A located?
Hemophilia is an inherited disease, most commonly affecting males, that is characterized by a deficiency in blood clotting. The responsible gene is
located on the X chromosome
, and since males inherit only one copy of the X chromosome, if that chromosome carries the mutated gene then they will have the disease.
Can hemophilia be cured?
There is currently no cure for hemophilia
. Effective treatments do exist, but they are expensive and involve lifelong injections several times per week to prevent bleeding.
What race is most affected by hemophilia?
The average age of persons with hemophilia in the United States is 23.5 years. Compared to the distribution of race and ethnicity in the U.S. population,
white race is more common
, Hispanic ethnicity is equally common, while black race and Asian ancestry are less common among persons with hemophilia.
What famous person has hemophilia?
The love of Elizabeth Taylor’s life and a Shakespearean actor for the ages,
Richard Burton
starred in 61 films and 30 plays — and was the first Hollywood star to reveal he had hemophilia. In fact, Burton and Taylor set up the Richard Burton Hemophilia Fund in 1964 to help find a cure for hemophilia.
Do females get hemophilia?
Hemophilia can affect women
, too
When a female has hemophilia, both X chromosomes are affected or one is affected and the other is missing or non-functioning. In these females, bleeding symptoms can be similar to males with hemophilia. When a female has one affected X chromosome, she is a “carrier” of hemophilia.
At what age is hemophilia diagnosed?
In the United States, most people with hemophilia are diagnosed at a very young age. Based on CDC data, the median age at diagnosis is
36 months for people with mild hemophilia
, 8 months for those with moderate hemophilia, and 1 month for those with severe hemophilia.
How long is the average lifespan of a person with hemophilia?
During this period, it exceeded mortality in the general population by a factor of 2.69 (95% confidence interval [CI]: 2.37-3.05), and median life expectancy in severe hemophilia was
63 years
.
Does hemophilia affect life expectancy?
Many patients still die before adulthood due to inadequate treatment. With proper treatment, life expectancy is only about
10 years less than healthy men
. Overall, the death rate for people with hemophilia is about twice that of the rate for healthy men. For severe hemophilia, the rate is four to six times higher.
Which type of hemophilia is more severe?
Hemophilia A
affects 1 in 5,000 to 10,000 males. Hemophilia B is less common, affecting 1 in 25,000 to 30,000 males. Around 60% to 70% of people with hemophilia A have the severe form of the disorder and about 15% have the moderate form. The rest have mild hemophilia.
What foods to avoid if you have hemophilia?
- large glasses of juice.
- soft drinks, energy drinks, and sweetened tea.
- heavy gravies and sauces.
- butter, shortening, or lard.
- full-fat dairy products.
- candy.
- foods containing trans fats, including fried. foods and baked goods (pastries, pizza, pie, cookies, and crackers)
What organs are affected by hemophilia?
Hemophilia can result in: Bleeding within joints that can lead to chronic joint disease and pain. Bleeding in the head and sometimes in
the brain
which can cause long term problems, such as seizures and paralysis. Death can occur if the bleeding cannot be stopped or if it occurs in a vital organ such as the brain.
Can hemophilia skip a generation?
Fact: Due to the genetic inheritance patterns of hemophilia,
the condition can skip a generation
, but it doesn’t always.
