Idiosyncratic reactions are unpredictable and not explained by the pharmacologic properties of the drug. An example is the
individual with infectious mononucleosis who develops a rash when given ampicillin
.
What is an idiosyncratic reaction?
Idiosyncratic drug reactions may be defined as
adverse effects that cannot be explained by the known mechanisms of action of the offending agent
, do not occur at any dose in most patients, and develop mostly unpredictably in susceptible individuals only.
What is an idiosyncratic drug response?
Idiosyncratic drug reactions, also known as type B reactions, are
drug reactions that occur rarely and unpredictably amongst the population
. This is not to be mistaken with idiopathic, which implies that the cause is not known.
Which response can be considered an idiosyncratic response?
Idiosyncrasy is an abnormal reactivity to a chemical that is peculiar to a given individual. It could be:
An abnormally exaggerated response
, or an abnormal lack of response. A response unusual because it requires an unusually small or unusually large dose.
What is a personal idiosyncrasy?
If a person has an idiosyncrasy, he or she has a little quirk, or
a funny behavior, that makes him or her different
. … Idio seems like it means stupid, but really it is Latin for “one’s own,” as an idiosyncrasy is one’s own particular, usually odd, behavior.
What is idiosyncratic toxicity?
Idiosyncratic toxicity can occur
when a convergence of risk factors
, including drug exposure, tips the risk-benefit balance away from benefit and toward risk.
What is the difference between a side effect and an adverse reaction?
Adverse events are unintended pharmacologic effects that occur when a medication is administered correctly while a side effect is a
secondary unwanted effect
that occurs due to drug therapy.
When an abnormal or unusual reaction to a drug?
An
adverse drug reaction (ADR)
is an injury caused by taking medication. ADRs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs.
When would you see an idiosyncratic response?
Idiosyncratic reactions are
unpredictable
and not explained by the pharmacologic properties of the drug. An example is the individual with infectious mononucleosis who develops a rash when given ampicillin.
What counts as an adverse event?
• An adverse event is
any untoward or unfavorable medical occurrence in a human
.
subject
, including any abnormal sign (for example, abnormal physical exam or. laboratory finding), symptom, or disease, temporally associated with the subject’s.
What is idiosyncrasy in medication administration?
An unusual response to a drug
. It can manifest as an accelerated, toxic, or inappropriate response to the usual therapeutic dose of a drug.
What is hypersensitivity reaction?
Hypersensitivity (also called hypersensitivity reaction or intolerance) refers
to undesirable reactions produced by the normal immune system
, including allergies and autoimmunity. They are usually referred to as an over-reaction of the immune system and these reactions may be damaging and uncomfortable.
What is allergy in pharmacology?
A drug allergy is
the abnormal reaction of your immune system to a medication
. Any medication — over-the-counter, prescription or herbal — is capable of inducing a drug allergy. However, a drug allergy is more likely with certain medications. The most common signs and symptoms of drug allergy are hives, rash or fever.
Does everyone have idiosyncrasy?
If you talk about the idiosyncrasies of someone or something, you are referring to their rather unusual habits or characteristics.
Everyone has a few little idiosyncrasies
.
What are idiosyncratic phrases?
Idiosyncratic language occurs
when the child uses standard words or phrases in an unusual
, but meaningful way (Volden & Lord, 1991). It is a broad term that can refer to a number of speech characteristics that are errors in the pragmatics of communication.
What does Idiocrasy mean?
:
peculiarity of constitution
: idiosyncrasy.
