Many studies have indicated that lisinopril (Zeneca's Zestril) and enalapril (Merck & Co's Vasotec) are equally potent in single daily doses for controlling mild to moderate hypertension.
What is the first drug of choice for hypertension?
The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.
Which ACE inhibitor is best for hypertension?
The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.
Which ACE inhibitor is best for blood pressure?
When considering factors such as increased ejection fraction, stroke volume, and decreasing mean arterial pressure, our results suggest that enalapril was the most effective ACE inhibitor.
What is the most popular ACE inhibitor?
However, there are many different ACE inhibitors, and you may wonder what the difference is between all of them. Three of the most popular are lisinopril, enalapril, and benazepril .
What is the safest blood pressure medication with the least side effects?
Thiazide diuretics generally have fewer side effects than the others. This is especially true when they're prescribed in the low doses that are generally used in treating early high blood pressure. Examples of thiazide diuretics include: chlorthalidone (Hygroton)
What is the safest BP medicine?
Methyldopa , which works to lower blood pressure through the central nervous system, has the lowest risk of harming the mother and developing fetus. Other possible safe options include labetalol, beta-blockers, and diuretics.
Why is lisinopril bad for you?
If it continues for a long time, the heart and arteries may not function properly . This can damage the blood vessels of the brain, heart, and kidneys resulting in a stroke, heart failure, or kidney failure.
What is a good replacement for lisinopril?
Losartan potassium is the generic name for the prescription drug commonly sold under the brand name Cozaar. Like lisinopril, it's approved by the FDA to treat high blood pressure, but it belongs to a different class of medications called angiotensin II receptor blockers (ARBs) (DailyMed, 2018).
What is a good replacement drug for lisinopril?
If you cannot take lisinopril or other ACE inhibitor medicines because of side effects such as a dry cough, you may be able to switch to another type of blood pressure-lowering medicine. This will usually be a medicine called an angiotensin receptor blocker, such as candesartan, irbesartan, losartan or valsartan .
Who should not take ACE inhibitors?
- Pregnant women. ...
- People with severe kidney failure. ...
- People who have ever had a severe allergic reaction that caused their tongue and lips to swell, even if it was from a bee sting, should not take ACE inhibitors.
Why are ACE inhibitors bad for you?
ACE inhibitors prevent an enzyme in the body from producing angiotensin II , a substance that narrows blood vessels. This narrowing can cause high blood pressure and forces the heart to work harder. Angiotensin II also releases hormones that raise blood pressure.
What is the difference between a beta blocker and an ACE inhibitor?
Beta-blockers treat many of the same conditions as ACE inhibitors, including high blood pressure, chronic heart failure, and stroke. Both types of medications also prevent migraines. Unlike ACE inhibitors, however, beta-blockers can help relieve angina (chest pain).
What is the safest blood pressure medicine for the elderly?
Angiotensin Receptor Blockers
ARBs are considered the alternative first-line treatment for hypertension in the elderly population when a diuretic is contraindicated. In elderly hypertensive patients with diabetes or HF, ARBs are considered first-line treatment and an alternative to ACE inhibitors.
What is the most common side effect of ACE inhibitors?
ACE inhibitors and bradykinin
ACE inhibitors block the breakdown of bradykinin, causing levels of this protein to rise and blood vessels to widen (vasodilation). Increased bradykinin levels are also responsible for the most common side effect of ACE inhibitor treatment; a dry cough .
What are the 4 worst blood pressure drugs?
- Atenolol. ...
- Furosemide (Lasix) ...
- Nifedipine (Adalat, Procardia) ...
- Terazosin (Hytrin) and Prazosin (Minipress) ...
- Hydralazine (Apresoline) ...
- Clonidine (Catapres)
