The Office of Laboratory Animal Welfare (OLAW)
is responsible for monitoring institutional compliance with PHS policy and guidelines.
Which PHS organization is responsible for monitoring organizational compliance with PHS Policy?
The Office for Protection from Research Risks (OPRR) of the National Institutes of Health (NIH)
develops, implements, and oversees compliance with the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (1).
Which individual is ultimately responsible for compliance with PHS Policy?
Responsibilities of the Institutional Official
While the institution is responsible for maintaining an Animal Care and Use Program that is in compliance with the PHS Policy and the AWRs,
the IO
is the individual held responsible on behalf of the institution for ensuring compliance.
Which of the following organizations must comply with the PHS Policy when utilizing?
Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? … Receipt of PHS funds requires compliance with the PHS Policy for
the Humane Care and Use of Laboratory Animals and the Guide
.
Who is given institutional responsibility for deciding if an individual researcher is properly trained to perform animal procedures as required by law?
Per PHS Policy and USDA Animal Welfare Regulations,
the IACUC
is given responsibility for ensuring that research personnel are properly trained to perform animal procedures.
Who benefits from the Iacuc’s activities to ensure compliance?
The IACUC’s activities to ensure compliance benefit whom?
The organization, investigators, animals, and public health and welfare
.
What are the 3 R’s in animal testing?
What are the 3Rs? The principles of the 3Rs (
Replacement, Reduction and Refinement
) were developed over 50 years ago providing a framework for performing more humane animal research.
What is not be an acceptable reason to justify multiple survival surgeries on an animal?
Whenever possible, all operative procedures should be done at one time to minimize post-operative discomfort and distress to the animal.
Cost or convenience
is not considered to be adequate justification for the conduct of multiple survival surgeries.
What are the laws that affect the use of animals in research teaching and testing?
The Animal Welfare Act (AWA)
is the federal law governing the care and use of laboratory animals in the United States. … The PHS Guide for the Care and Use of Laboratory Animals sets the standards for care and housing that must be provided for animals in PHS-funded studies.
What are three components that must be described in the Animal Welfare Assurance?
Components of the institution that will be covered by the Assurance.
Institutional commitment to the Animal Welfare Act, the U.S. Government Principles and the Guide for the Care and Use of Laboratory Animals
.
Description of program for animal care and use
.
Program evaluation and accreditation
.
Which institutions must follow PHS guidelines for animal research?
Passed by Congress in 1985, the Health Research Extension Act directed the PHS to provide guidelines for animal research.
The Office of Laboratory Animal Welfare (OLAW)
is responsible for monitoring institutional compliance with PHS policy and guidelines.
Which activity would place a study in pain Category B?
Category B animals are those that are being “bred”, conditioned, or held for use in teaching, testing, experiments, research, or
surgery
but not yet used for such purposes.” These animals have not been used for any research procedure, however minor.
In which of the following ways is an Institutional Animal Care and Use Committee?
In which of the following ways is an institutional animal care and use committee (IACUC) different from an institutional review board (IRB)? … IACUCs
monitor the care and treatment of animals
throughout the study; IRBs do not monitor the care of human participants throughout the study.
Who enforces PHS Policy?
The PHS Policy has been law since 1985, and is enforced by
the Office of Laboratory Animal Welfare (OLAW) of the National Institutes of Health (NIH)
.
Who appoints the members of the Iacuc?
1.
The Institutional Official
appoints members to standing university research committees and, as authorized by the President, appoints the Chair and members to the IACUC. Approximately once a year, the DRECS submits recommendations for membership to the Institutional Official.
What is the primary purpose of the 3 Rs concept?
The primary purpose of the “3 Rs” is
to urge investigators to minimize use of animals and minimize pain and distress caused by animal research
.
