Can CLL Cause Low White Blood Cell Count?

by | Last updated on January 24, 2024

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Can CLL cause low white blood cell count? low platelet counts

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How does CLL affect white blood cells?

Chronic lymphocytic leukemia (CLL) is a malignant blood disorder in which there are an

increased number of white blood cells in the lymphoid tissue

. In CLL, the abnormal lymphocytes, also called leukemic cells, are produced instead of healthy white blood cells, and then accumulate over time.

Does leukemia cause low WBC?


Leukemia can also present with very low white blood cell counts

, because the immature cells get trapped in the bone marrow and are not detected in blood tests.

What WBC count indicates CLL?

Effects of Too Many White Blood Cells

Typically a healthy person has a white blood cell count of about 4,000-11,000. Patients with acute or even chronic leukemia may come in with a white blood cell count up into the

100,000-400,000

range.

Can WBC fluctuate with CLL?

Answer from Dr. Leclair: Oh my,

yes, those changes are possible for CLL folks

. They are especially annoying if you have allergies or a mild viral infection or recent trauma (one person I know fell off his bike, scraping his leg, and his WBC doubled).

How do I know if my CLL is getting worse?


Unexplained weight loss of more than 10 percent of your body weight over the course of 6 months or so

could mean your CLL is progressing. This means that you’re losing weight when you’re not trying to diet.

What type of leukemia causes low white blood cells?

Many signs and symptoms of

AML

are the result of a shortage of normal blood cells, which happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets.

What is the most common reason for low white blood cell count?

A low white blood cell count usually is caused by:

Viral infections that temporarily disrupt the work of bone marrow

. Certain disorders present at birth (congenital) that involve diminished bone marrow function. Cancer or other diseases that damage bone marrow.

What are the symptoms of low white blood cell count?

The common symptoms of a low WBC, also known as leukopenia, include

body aches, chills, fever and headaches

. If you have these symptoms, please schedule an appointment with your doctor and he/she may recommend a WBC count.

What would a CBC look like with leukemia?

Understanding your blood count test results

If you have leukemia, your blood cells count will likely show

higher than usual levels of white blood cells, which include leukemic cells

. You may also have lower than usual red blood cell and platelet cell counts. If all three types are low, this is known as pancytopenia.

What labs are abnormal with CLL?

People with CLL have

too many lymphocytes

. (This may be called lymphocytosis.) Having more than 10,000 lymphocytes/mm3 (per cubic millimeter) of blood strongly suggests CLL, but other tests are needed to know for sure. You might also have low levels of red blood cells and platelets.

How long can you have chronic leukemia without knowing?

In CLL, the leukemia cells grow out of control and crowd out normal blood cells. These cells often build up slowly over time. Many people don’t have any symptoms for

at least a few years

. In time, the cells can spread to other parts of the body, including the lymph nodes, liver, and spleen.

Is CLL ever misdiagnosed?

Leukemia Misdiagnosis

Physicians often fail to diagnose chronic leukemia, as it often shows no symptoms until the disease has begun to progress.

Many of the symptoms of leukemia may also be symptoms of other illnesses, which results in a high number of misdiagnoses

.

What vitamins should I take if I have CLL?

In patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), high doses of

curcumin and vitamin D

could help stabilize the disease, according to new research presented at the American Society of Hematology’s (ASH) Annual Meeting in San Diego.

At what point does CLL require treatment?

Patients with chronic lymphocytic leukemia (chronic lymphoid leukemia, CLL) do not require drug therapy

until they become symptomatic or display evidence of rapid progression of disease

, as characterized by the following: Weight loss of more than 10% over 6 months. Extreme fatigue.

What are high numbers for CLL?

A normal lymphocyte range for adults is anywhere between 1,000 and 4,800 cells in 1 microliter (μl) of blood. A diagnosis of chronic lymphocytic leukemia requires a lymphocyte level of

greater than or equal to 5,000 B cells per μl for a minimum of 3 months

.

What are the four complications of CLL?

  • Frequent infections. If you have chronic lymphocytic leukemia, you may experience frequent infections that can be serious. …
  • A switch to a more aggressive form of cancer. …
  • Increased risk of other cancers. …
  • Immune system problems.

What does CLL fatigue feel like?

In general, the fatigue associated with CLL tends to: make it difficult or impossible to do what you used to do in a day.

make you feel weak and completely out of energy

. not go away even if you are getting enough sleep.

What is the life expectancy of someone with CLL?

The prognosis of patients with CLL varies widely at diagnosis. Some patients die rapidly, within 2-3 years of diagnosis, because of complications from CLL. Most patients live

5-10 years

, with an initial course that is relatively benign but followed by a terminal, progressive, and resistant phase lasting 1-2 years.

Which is worse CLL or CML?

Symptoms CML CLL Easy and unexplained bruising x x Enlarged lymph nodes x x Infections x x A feeling of fullness in your stomach x

Does CLL affect the brain?

Leptomeningeal disease as an initial presentation of untransformed CLL is exceedingly rare. However

a large autopsy study reported brain and leptomeningeal involvement in 20% and 8% of cases, respectively

,

4

suggesting that CNS involvement in patients with CLL is underdiagnosed.

What foods to avoid if you have low white blood cells?

If you have neutropenia, you should avoid raw meat, eggs and fish, moldy or expired food, unwashed or moldy fruit and vegetables, and unpasteurized beverages, including fruit and vegetable juice, beer, milk, as well as unpasteurized honey. Fruits and Vegetables should be washed thoroughly before you eat them.

Should I be worried about low white blood cell count?


A truly low white blood cell count also puts you at higher risk for infections

— typically bacterial infections. But viral infections also may be a concern. To help reduce your infection risk, your doctor may suggest you wear a face mask and avoid anyone with a cold or other illness.

When should I be worried about low white blood cells?

How many white blood cells (WBCs) someone has varies, but the normal range is usually between 4,000 and 11,000 per microliter of blood.

A blood test that shows a WBC count of less than 4,000 per microliter (some labs say less than 4,500) could mean your body may not be able to fight infection the way it should.

What diseases cause low white blood cell count?

A low white blood cell count can be an indicator of certain conditions, including

lupus, rheumatoid arthritis, vitamin deficiencies, or a side effect of cancer treatment

.

How do you fix low white blood cell count?

  1. Antibiotics to treat any infections.
  2. Medicines to push your body to make more white blood cells.
  3. Treatment for any diseases that may be causing the count to be low.

Can anxiety cause low white cell count?

Calabrese says. In addition,

stress decreases the body’s lymphocytes

— the white blood cells that help fight off infection. The lower your lymphocyte level, the more at risk you are for viruses, including the common cold and cold sores.

Can low white blood cells be cured?

Depending on the cause,

leukopenia can be treated in several ways

. While your WBC count is low, you can also make dietary and lifestyle changes to help reduce your risk of infection. If you have leukopenia and symptoms of an infection, contact your doctor right away.

What clues on a CBC would make a doctor suspect leukemia?

What bloodwork shows leukemia?

A

complete blood count (CBC)

is a common blood test that your doctor may recommend to: Help diagnose some blood cancers, such as leukemia and lymphoma.

What labs are abnormal in leukemia?

Your doctor will conduct a complete blood count (CBC) to determine if you have leukemia. This test may reveal if you have leukemic cells.

Abnormal levels of white blood cells and abnormally low red blood cell or platelet counts

can also indicate leukemia.

What are markers in CLL?

Is CLL a death sentence?

CLL is

not an imminent death sentence

, especially now. A significant chunk of us will never need treatment and even more of die with the disease, not from it.

Can CLL go into remission?


CLL can be in remission for many years, but there’s always a possibility it will come back

. This is called a recurrence.

Can you live 20 years with CLL?

CLL has a very high incidence rate in people older than 60 years. CLL affects men more than women.

If the disease has affected the B cells, the person’s life expectancy can range from 10 to 20 years

.

What percentage of CLL patients never need treatment?

Around

30-50%

of people diagnosed with CLL never require any treatment for their disease and can survive for many years despite their diagnosis.

James Park
Author
James Park
Dr. James Park is a medical doctor and health expert with a focus on disease prevention and wellness. He has written several publications on nutrition and fitness, and has been featured in various health magazines. Dr. Park's evidence-based approach to health will help you make informed decisions about your well-being.