Adults—75 to 150 milligrams (mg) per day, divided into three or four equal doses, and taken for 1 to 2 weeks as determined by your doctor.
What are the long term effects of taking indomethacin?
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs may increase your risk of heart attack, heart failure, or stroke . This risk may be higher if you’re taking it long term, at high doses, or if you already have heart problems or risk factors for heart disease, such as high blood pressure.
Can indomethacin cause liver damage?
Drug induced liver injury from indomethacin is usually mild-to-moderate in severity and transient, but can progress to acute liver failure and death . In large case series, indomethacin is rarely mentioned as a cause of acute liver failure. Rechallenge may lead to recurrence and should be avoided.
What does indomethacin do to your body?
Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis . It is also used to relieve pain from various other conditions. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).
What is the side effect of indomethacin?
Serious side effects of Indocin may include heart attack, stroke , skin changes (paleness, blisters, rash, and hives), weight gain, swelling, shortness of breath, tachycardia, unusual bleeding (including GI bleeding), jaundice, stomach pain, and pain with urination, bloody urine, blurry vision, and back pain.
Is indomethacin a good painkiller?
Indomethacin is a nonsteroidal anti-inflammatory drug with potent antipyretic, analgesic, and anti-inflammatory activity that has been effectively used in the management of mild-to-moderate pain since the mid-1960s.
Can you drink coffee with indomethacin?
If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use.
Is indomethacin a safe drug?
Indomethacin can increase your risk of fatal heart attack or stroke, even if you don’t have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal.
Can I take indomethacin every day?
Adults— 25 milligrams (mg) two or three times a day . Your doctor may increase your dose by 25 or 50 mg per day, as needed. However, the total dose is usually not more than 200 mg per day. Children 15 years of age and older—Dose is based on body weight and must be determined by your doctor.
Does indomethacin make you sleepy?
This medicine may cause some people to become dizzy, lightheaded, drowsy , or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising.
Is indomethacin stronger than ibuprofen?
Indocin (indomethacin) works well for mild to moderate pain and swelling, but it shouldn’t be used long-term since it has some serious side effects. Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
Does indomethacin cause depression?
The central nervous system (CNS) side effects of indomethacin include cognitive dysfunction, depression depersonalisation , hallucination, and psychosis.
Will indomethacin raise blood pressure?
The most widely studied of the NSAID medications is indomethacin, which has been shown to increase mean blood pressure by as much as 5 mm Hg in treated hypertensive patients.
What drug is similar to indomethacin?
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that reduces fever, pain and inflammation. It is similar to ibuprofen (Motrin) and naproxen (Naprosyn
What drugs interact with indomethacin?
Some products that may interact with this drug include: aliskiren , ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as valsartan, losartan), cidofovir, corticosteroids (such as prednisone), lithium, methotrexate, “water pills” (diuretics such as furosemide).
Can I have a glass of wine while taking indomethacin?
Do not drink alcohol while taking indomethacin . Alcohol can increase your risk of stomach bleeding caused by indomethacin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.
