Epinephrine is
contraindicated for angle-closure glaucoma
and should be used with caution in patients with narrow angles. Although there is a potential for serious systemic side effects, most of the recognized side effects are not serious and are reversible with drug discontinuation.
Which drug is contraindicated in angle-closure glaucoma?
Sulfa-based drugs (
acetazolamide
, hydrochlorothiazide, cotrimoxazole, and topiramate) can cause acute angle closure glaucoma by ciliary body edema with anterior rotation of the iris-lens diaphragm. Iridotomy is not effective.
Why is epinephrine contraindicated in closed angle glaucoma?
These agents stimulate both alpha-1 and alpha-2 adrenergic receptors, thus topical administration
How does epinephrine treat glaucoma?
What is epinephrine ophthalmic? Epinephrine ophthalmic (for the eyes)
reduces
the amount of fluid in the eye, which decreases pressure inside the eye. Epinephrine ophthalmic is used to treat glaucoma and is also used during eye surgery.
What medications should be avoided with narrow angle glaucoma?
What medicines should patients with Narrow Angle Glaucoma avoid? Patients with Narrow Angle Glaucoma should avoid cold remedies which contain
Pseudoephedrine, Phenylephrine or Neo-Synephrine
; anti-histaminics Chlorpheniramine, Diphenhydramine or Benadryl and overactive bladder remedies such as Detrol.
Which drug can cause open angle glaucoma?
The classes of medications that have the potential to induce angle closure are
topical anticholinergic
or sympathomimetic dilating drops, tricyclic antidepressants, monoamine oxidase inhibitors, antihistamines, antiparkinsonian drugs, antipsychotic medications, and antispasmolytic agents.
What Should glaucoma patients avoid?
You should avoid foods like
baked goods such as cookies, cakes, donuts
or fried items like French fries or stick margarine to steer clear from worsening your glaucoma. It may also improve your eye health.
Why is epinephrine contraindicated in aphakic glaucoma?
Epinephrine is avoided
because of the risk of macular edema
. Ultimately, iridotomy usually is needed in both cases. In aphakia, the iridotomy must be placed over a pocket of aqueous behind the iris, and this may require multiple attempts.
Why adrenaline is contraindicated in glaucoma?
These agents stimulate both alpha-1 and alpha-2 adrenergic receptors, thus topical administration can induce transient mydriasis, either with or without the use of concomitant miotic agents. In patients with narrow angles, any degree of pupillary dilation can provoke an acute attack of angle-closure glaucoma.
Why is atropine contraindicated in glaucoma?
Antimuscarinics such as atropine are contraindicated in angle-closure glaucoma because of
the increased likelihood of producing complete obstruction of the outflow of aqueous humor
, resulting in an acute increase in intraocular pressure (IOP) in response to relaxation of the ciliary muscle.
Is epinephrine bad for glaucoma?
Epinephrine and pilocarpine ophthalmic
should not be used to treat narrow- or shallow-angle glaucoma
. Rarely, pilocarpine ophthalmic may cause retinal detachment.
What is the drug of choice for glaucoma?
Brimonidine
.
Brimonidine
is the a-2 agonist of choice in glaucoma treatment, which acts by decreasing the aqueous humor secretion and increasing the uveoscleral outflow.
Does atropine treat glaucoma?
Atropine sulfate is used in the eye to dilate the pupil. It may also be used to control pain in the eye due to corneal and uveal disease and in
treating secondary glaucoma
.
Can you go blind from narrow angle glaucoma?
Each Narrow Angle Glaucoma episode has the power to affect your peripheral vision, meaning
vision loss can happen
as a result. Narrow Angle Glaucoma can be more episodic and worsen slowly, which makes the eye condition leave unanticipated damage.
Does sleep position affect eye pressure?
Conclusion. Lateral and prone sleeping positions
usually do result in significant elevations of IOP in PD patients
. Dependency status did not make a difference. A significantly larger IOP increase was seen in the prone position than in the lateral position.
What is the safest eye drop for glaucoma?
Next came
apraclonidine
, brand name Iopidine, marketed by Alcon. I did much of the clinical work on apraclonidine, a relatively selective alpha-2 agonist. It is probably the safest drug we have seen so far in the therapy of glaucoma.
