Divalproex sodium, valproate sodium, and valproic acid, are all similar medications that are used by the body as valproic acid . Therefore, the term valproic acid will be used to represent all of these medications in this discussion.
What is the difference between valproic acid and divalproex?
Valproic acid is metabolized more rapidly than divalproex sodium , which could explain the need for higher doses. However, even at higher doses, treatment with valproic acid is still less expensive than with divalproex sodium because of the difference in price.
Are valproic acid and divalproex interchangeable?
Divalproex is converted to valproic acid in the body , and the two medications are very similar. Some patients may find that divalproex is easier on the stomach than valproic acid. Note: both medications are referred to as “valproic acid” in this document.
What is another name for valproic acid?
Valproic (val-PRO-ik) acid is the generic name (non-brand name) of a widely used type of seizure medicine. The brand-name form of valproic acid in the United States and Canada is Depakene . In the UK, it is Convulex. Brand names used in other countries include Depakine, Orfiril, Valporal, and Valprosid.
What is the difference between Depakote and divalproex?
What Is Depakote? Depakote (divalproex sodium) is a stable coordination compound comprised of sodium valproate and valproic acid used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches. Generic Depakote (termed divalproex sodium) is available under several other names.
What is comparable to Depakote?
Lamictal (lamotrigine) and Depakote (divalproex sodium) are antiepileptic drugs (AEDs), also called anticonvulsants, used alone or in combination with other antiseizure medications for treating certain types of seizures.
What is the generic name for divalproex?
Depakote (divalproex sodium) is a stable coordination compound comprised of sodium valproate and valproic acid used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches. Generic Depakote (termed divalproex sodium) is available under several other names.
Can I take naproxen with valproic acid?
Interactions between your drugs
No interactions were found between Depakote and naproxen. This does not necessarily mean no interactions exist.
What medications contain valproic acid?
- Depakene.
- Depakote.
- Depakote DR.
- Depakote ER.
- Depakote Sprinkles.
- Stavzor.
What is the other name for carbamazepine?
Carbamazepine, Oral Tablet. Carbamazepine oral tablet is available as brand-name drugs and as a generic drug. Brand names: Tegretol, Tegretol XR, Epitol .
Is divalproex a narcotic?
Is divalproex a narcotic? No, divalproex isn’t a narcotic . Divalproex belongs to a group of drugs called antiepileptics.
Is divalproex the same as lithium?
Divalproex was as effective in rapid-cycling manic patients as in other patients. Conclusions: Both divalproex and lithium were significantly more effective than placebo in reducing the symptoms of acute mania. The efficacy of divalproex appears to be independent of prior responsiveness to lithium.
Is valproate the same as Depakote?
A closely related medication, Depakene (valproic acid), comes in capsule and liquid form. Another variety of valproic acid, Stavzor, is no longer manufactured. In 2008, the FDA approved the first generic version of Depakote . Collectively, these medications are known as valproate products.
Can divalproex be cut in half?
Swallow the extended-release tablet or tablet whole with a full glass of water. Do not split, crush , or chew it. Part of the medicine may pass into your stool after your body has absorbed the medicine. Check with your doctor right away if this happens.
Is divalproex for bipolar?
DEPAKOTE ® (divalproex sodium) delayed-release tablets, for oral use, is a valproate and is indicated for the treatment of the manic episodes associated with bipolar disorder . A manic episode is a distinct period of abnormally and persistently elevated, expansive, or irritable mood.
Is divalproex the same as Keppra?
And well my seizures have stopped with the Depakote, but as I said side effect...
Which is safer lithium or Depakote?
Patients taking lithium had lower rates of self-harm and unintentional injury compared to those taking other bipolar drugs, such as valproate (Depacon, Depakote), olanzapine (Zyprexa) or quetiapine (Seroquel), said lead researcher Joseph Hayes.
Why Depakote is bad for you?
Side effects of Depakote and Depakote ER can be serious and sometimes deadly. Depakote side effects include liver damage , life-threatening pancreatitis, suicidal thoughts, and blood and metabolic disorders. When women take Depakote during pregnancy, their children have a higher risk of birth defects.
Is Depakote the same as Keppra?
Are Keppra and Depakote the Same Thing? Keppra (levetiracetam) and Depakote (divalproex sodium) are anti-epileptic drugs (AEDs) (anticonvulsants) used to treat seizures in people with epilepsy. Keppra is often used in conjunction with other drugs.
Is divalproex safe?
Divalproex sodium can cause liver failure that may be fatal , especially in children under age 2 and in people with liver problems caused by certain genetic disorders.
Who should not take valproic acid?
You should not use valproic acid if you are allergic to it, or if you have: liver disease ; a urea cycle disorder; or. a genetic mitochondrial (MYE-toe-KON-dree-al) disorder such as Alpers’ disease or Alpers-Huttenlocher syndrome, especially in a child younger than 2 years old.
What drugs should not be taken with valproic acid?
Some products that may interact with this drug include: certain antidepressants (e.g., amitriptyline, nortriptyline, phenelzine), certain antibiotics (carbapenems such as doripenem, imipenem), irinotecan, mefloquine, orlistat, other medications for seizure (e.g., ethosuximide, lamotrigine, phenytoin, rufinamide, ...
Is valproic acid an antipsychotic?
Mood stabilizers (e.g., valproic acid) and antipsychotic drugs (APDs) are commonly co-administered in the treatment of bipolar disorder and schizophrenia. The basis for any synergism between these classes of drugs in either group of disorders has been little studied.
What medications should be stopped before ECT?
Medication Information:
Benzodiazepines, Depakote, Lamictal, Neurontin, Trileptal – Do not take the night time dose or morning dose before your treatment. Lithium – Do not take for 24 hours before each treatment. Glucophage/Metformin – Do not take for 12 hours before each treatment.
Can you take Tylenol with valproic acid?
No interactions were found between Tylenol and valproic acid.
Is valproic acid an antidepressant?
Valproic acid, beside its anticonvulsant action, is widely used as a mood stabilizer in the therapy of bipolar disorder. The potential antidepressant action of valproic acid has not been sufficiently characterized so far.
What is the trade name of valproate?
Sodium valproate Brand names: Dyzantil , Epilim, Episenta, Epival.
What is similar to carbamazepine?
Gabapentin is an anti-epileptic drug that is structurally related to the neurotransmitter GABA. This drug is almost as effective as carbamazepine but involves fewer side effects. The starting dose is usually 300mg three times a day and this is increased to a maximal dose.
What is the generic name for carbamazepine?
Tegretol (carbamazepine) is an anticonvulsant used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy.
Is valproic acid the same as Depakene?
Valproic acid is an antiepileptic used to treat various types of seizure disorders. Valproic acid is sometimes used together with other seizure medications. Valproic acid is available under the following different brand names: Depakene, Stavzor, and Depacon.
What’s the other name for Keppra?
Levetiracetam (lev-eh-teer-ASS-eh-tam) is the generic name (non-brand name) for the drug called Keppra (KEP-ruh). Keppra is a widely used seizure medicine from UCB.
Is carbamazepine the same as TEGretol?
Tegretol, generic name carbamazepine , is an anticonvulsant that is sometimes prescribed as a mood stabilizer in bipolar disorder. In addition to seizures and bipolar disorder, it’s also prescribed for pain relief in trigeminal neuralgia.
Can divalproex cause seizures?
We again urge patients and families to contact their doctor before stopping an epilepsy medication because this may possibly lead to seizures and worsening of mood. See package insert. Besides the treatment of seizures, Depakote is also indicated for: treatment of manic episodes associated with bipolar disorder.
Is 500 mg of divalproex a lot?
Depakote ER is indicated for prophylaxis of migraine headaches in adults. The recommended starting dose is 500 mg once daily for 1 week , thereafter increasing to 1000 mg once daily.
Does divalproex cause memory loss?
Divalproex treatment was associated with accelerated brain volume loss over 1 year and perhaps with greater cognitive impairment. The long-term clinical effects of these changes are not known.
Can you take valproic acid with lithium?
Lithium and valproic acid are the most commonly used mood-stabilizing agents. The combination of lithium and valproate appears to be well tolerated and effective in treating bipolar illness .
Can you take lithium and valproic acid together?
Conclusion: Concomitant administration of lithium and valproate appears to be safe in patients with bipolar disorder .
What are the side effects of divalproex?
- Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), unsteadiness, weight changes may occur. ...
- You may rarely see partial tablets in your stool.
