High doses or long-term use of olanzapine can cause a serious movement disorder that may not be reversible . The longer you use olanzapine, the more likely you are to develop this disorder, especially if you are a woman or an older adult.
What are the long-term side effects of olanzapine?
- Drowsiness.
- Restlessness.
- Dizziness.
- Depression.
- Trouble sleeping.
- Unusual behavior.
- Constipation.
- Trouble walking.
Is olanzapine a safe drug?
Conclusion: These results show that olanzapine is safe and effective in nonselected schizophrenic outpatients and are consistent with the efficacy and safety profile that olanzapine has shown in previous controlled clinical trials.
What does olanzapine do to the brain?
The main effect that olanzapine has is to block some dopamine receptors in the brain , correcting the overactivity of dopamine. Olanzapine also has effects on other neurotransmitters in the brain such as serotonin (5-HT), which may also contribute to its beneficial effects.
Can olanzapine be taken long-term?
Schizophrenia requires long-term treatment. Do not stop taking olanzapine , even when you feel better. With input from you, your health care provider will assess how long you will need to take the medicine. Missing doses of olanzapine may increase your risk for a relapse in your symptoms.
Does olanzapine cause brain damage?
Sustained use of the antipsychotic olanzapine in patients with remitted psychotic depression was associated with a thinning of the cortex , when compared with placebo, according to a study published online in JAMA Psychiatry.
Can olanzapine change your personality?
• This medication will not change your personality .
It will help to reduce repetitive thoughts, which cause anxiety.
Does olanzapine affect your memory?
In contrast, olanzapine had significant sedative effects . Moreover, the subjects displayed a significant impairment on all measures of psychomotor function and verbal memory, which was not attributable to the drug’s sedative effects.
Does olanzapine make you pee a lot?
Hyperglycemia (high blood sugar). Symptoms can include: frequent urination . increased thirst .
Does olanzapine help anxiety?
Atypical antipsychotics such as quetiapine, aripiprazole, olanzapine, and risperidone have been shown to be helpful in addressing a range of anxiety and depressive symptoms in individuals with schizophrenia and schizoaffective disorders, and have since been used in the treatment of a range of mood and anxiety disorders ...
Is 15 mg of olanzapine a lot?
The recommended starting dose for Olanzapine Accord is 10mg/day. The starting dose is 15mg as a single daily dose in monotherapy or 10mg daily in combination therapy (see section 5.1). The recommended starting dose is 10mg/day.
What is the side effect of olanzapine?
Drowsiness, dizziness, lightheadedness, stomach upset, dry mouth, constipation, increased appetite, or weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Dizziness and lightheadedness can increase the risk of falling.
Is 5mg of olanzapine a lot?
Gradual tapering of the dose should be considered when discontinuing olanzapine. A lower starting dose (5 mg/day) is not routinely indicated but should be considered for those 65 and over when clinical factors warrant (see section 4.4). A lower starting dose (5 mg) should be considered for such patients.
How much olanzapine is fatal?
Fatal outcomes have been reported for acute overdoses as low as 450 mg but survival has also been reported following acute overdose of approximately 2 g of oral olanzapine.
How long does olanzapine stay in your system?
How long does olanzapine stay in my body? Individuals break down medications at different rates. On average, it takes up to seven days for most of the olanzapine to be gone from the body. Before making any changes to your medication, talk with your health care provider about the benefits and risks.
How long do you sleep on olanzapine?
Olanzapine is a great sleep aid alternative to addictive sleep medication. I take 5mg at night and I sleep 8 – 10 hours without waking up throughout the night (I used to sleep 5 – 6 hours and waking up several times). For the first couple of weeks you’ll feel groggy and be hungry but these side effects will go away.
