How Does Contractility Affect End Diastolic Volume?
How Does Contractility Affect End Diastolic Volume? Increased heart rate alone decreases stroke volume because of reduced time for diastolic filling, which decreases end-diastolic volume. How does contractility affect EDV? Briefly, an increase in venous return to the heart increases the filled volume (EDV) of the ventricle, which stretches the muscle fibers thereby increasing their