What Is Considered A Narrow Therapeutic Index?

What Is Considered A Narrow Therapeutic Index? • Narrow therapeutic index (NTI) drugs are defined as those drugs where. small differences in dose or blood concentration may lead to dose and blood concentration dependent, serious therapeutic failures or adverse drug reactions. Is high therapeutic index Good or bad? The larger the TI, the safer the

What Is The MEC Of A Drug?

What Is The MEC Of A Drug? Minimum effective concentration (MEC) is the minimum plasma concentration of a drug needed to achieve sufficient drug concentration at the receptors to produce the desired pharmacologic response, if drug molecules in plasma are in equilibrium with drug molecules in the various tissues (Figure 1.3). How do I get