Why Does Unconjugated Bilirubin Increase In Hepatic Jaundice?

Why Does Unconjugated Bilirubin Increase In Hepatic Jaundice? In prehepatic jaundice, excess unconjugated bilirubin is produced faster than the liver is able to conjugate it for excretion. The liver can excrete six times the normal daily load before bilirubin concentrations in the plasma rise. Unconjugated bilirubin is insoluble and is not excreted in the urine.

Is High Indirect Bilirubin Dangerous?

Is High Indirect Bilirubin Dangerous? Elevated levels may indicate liver damage or disease. Higher than normal levels of direct bilirubin in your blood may indicate your liver isn’t clearing bilirubin properly. Elevated levels of indirect bilirubin may indicate other problems. Is indirect bilirubin dangerous? Infant jaundice In an infant, high (usually indirect) bilirubin and jaundice