Why Does Unconjugated Bilirubin Increase In Hepatic Jaundice?
Why Does Unconjugated Bilirubin Increase In Hepatic Jaundice? In prehepatic jaundice, excess unconjugated bilirubin is produced faster than the liver is able to conjugate it for excretion. The liver can excrete six times the normal daily load before bilirubin concentrations in the plasma rise. Unconjugated bilirubin is insoluble and is not excreted in the urine.