Will Lupus Affect Menstrual Cycle?

Will Lupus Affect Menstrual Cycle? Lupus can disrupt the menstrual cycle as flare-ups interfere with normal hormone processes. “When patients are really inflamed, it can affect the hypothalamic-pituitary-adrenal axis,” Grossman says. Does lupus make your period worse? Some women with lupus report their symptoms become worse during menstruation and pregnancy and with the use of