Can Lupus Affect A Woman’s Menstrual Cycle?

Can Lupus Affect A Woman’s Menstrual Cycle? Lupus can disrupt the menstrual cycle as flare-ups interfere with normal hormone processes. “When patients are really inflamed, it can affect the hypothalamic-pituitary-adrenal axis,” Grossman says. Can lupus affect your uterus? In lupus, the immune system may attack and destroy the corpus luteum, which means the uterus doesn’t