How Does The Mushroom Toxin Alpha Amanitin Inhibits The Process Of Transcription?

How Does The Mushroom Toxin Alpha Amanitin Inhibits The Process Of Transcription? Mode of inhibitory action From the crystal structure solved by Dr. Bushnell et al., α-Amanitin interacts with the bridge helix in RNA polymerase II (pol II). This interaction interferes with the translocation of RNA and DNA needed to empty the site for the