How Do You Know If A Protein Binds To DNA?

How Do You Know If A Protein Binds To DNA? Chromatin immunoprecipitation is used to identify the in vivo DNA target regions of a known transcription factor. … Yeast one-hybrid System (Y1H) is used to identify which protein binds to a particular DNA fragment. Bacterial one-hybrid system (B1H) is used to identify which protein binds