- Pale coloring, including loss of pink color in cheeks and inside the lower eyelids.
- Extreme fatigue.
- Shortness of breath.
- Easy bruising or unexplained bruises.
- Unusual bleeding, such as bleeding from the nose and mouth.
- Decreased urination or blood in the urine.
How long does hemolytic uremic syndrome last?
It may last as long as
7 to 10 days
. What type of treatment should I expect for my child? If symptoms are mild, no treatment is needed. Sometimes, children with HUS have to stay in the hospital.
How do you know if you have HUS?
Symptoms of HUS include
vomiting and diarrhea (often bloody), weakness, lethargy, and bruising (purpura)
. These symptoms are due to a combination of dehydration, anemia (due to the destruction of red blood cells and low platelet counts), and uremia (the inability of the kidneys to clear waste products from the body).
Who gets hemolytic uremic syndrome?
coli(STEC) strain can get HUS. Children who are
less than 5 years old
, people with weakened immune systems (such as those with cancer, HIV/AIDS, or a transplant), or persons with a family history of HUS are more at risk to develop the disease.
What is the treatment for hemolytic uremic syndrome?
HUS is generally treated with
medical care in the hospital
. Close attention to fluid volume is very important. This potentially includes intravenous (IV) fluids and nutritional supplementation by IV or tube feeding. A transfusion of blood may also be needed.
How serious is HUS?
Hemolytic uremic syndrome (HUS) is a condition that can occur when the small blood vessels in your kidneys become damaged and inflamed. This damage can cause clots to form in the vessels. The clots clog the filtering system in the kidneys and lead to
kidney failure
, which could be life-threatening.
What drugs can cause HUS?
Cisplatin
, one of the most frequently used antineoplastic drugs, also induces HUS. Cyclosporin causes HUS, probably due to endothelial damage and/or an inhibition of prostacyclin synthesis. A case of FK506 induced HUS has been recently reported. Quinine and Cocaine also can induce HUS.
What is the main reason for hemolytic uremic syndrome?
What causes HUS? Most cases of HUS occur after an infection in the digestive tract caused by the E. coli bacterium, O157:H7.
Diarrhea and upper respiratory infections
are the most common factors leading to HUS.
How is hemolytic uremic syndrome transmitted?
HUS cannot be spread from person-to-person. However, STEC, Shigella and other organisms that can cause HUS can be spread through
eating or drinking contaminated food or water or contact with a person who is ill
.
How can HUS be prevented?
- Wash your hands.
- Cook and serve your food at the appropriate temperatures.
- Keep your food preparation areas clean.
- Avoid unpasteurized beverages.
- Serve irradiated hamburger.
- Be careful when dealing with animals.
Can HUS cause liver damage?
During the recovery stage of the hemolytic uremic syndrome in 2 cases an increase of serum levels of GOT, GPT, LDH, gammaGT, 5’ND and AP was noticed, without signs of a recurrence of the disease. In one patient also jaundice and hepatomegaly were found. The observations suggest a parenchymal damage of the liver.
Can E coli affect the kidneys?
A bacteria called Escherichia Coli (E Coli) causes
about 90 percent of kidney infections
. The bacteria migrate from the genitals through the urethra (the tube that removes urine from the body) into the bladder and up the tubes (ureters) that connect the bladder to the kidneys.
How do you get uremic poisoning?
If your kidneys don’t work
well
, those things can stay in your blood. That condition is called uremia, or uremic syndrome. It can happen because of a long-running health problem, like diabetes or high blood pressure, or because a severe injury or an infection damages your kidneys.
Why do HUS not take antibiotics?
Additionally, antibiotic-induced injury to the bacterial membrane favors the acute release of large amounts of toxins. Use of antibiotics has been shown to increase the risk of full-blown HUS by 17-fold, and thus, the recommendation is to avoid its use,
except in cases of sepsis
.
How common is HUS in adults?
Typical hemolytic uremic syndrome (HUS) in adults is
an uncommon clinical occurrence
and has been rarely reported in the literature. Typical HUS is mainly caused by Shiga toxin-producing Escherichia coli (STEC) and is typically a pediatric disease.
Is hemolytic anemia genetic?
Hemolytic anemia
can be inherited or acquired
: Inherited hemolytic anemia happens when parents pass the gene for the condition on to their children. Acquired hemolytic anemia is not something you are born with. You develop the condition later.
