Streptomycin is an aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
What bacteria does streptomycin target?
Streptomycin is a member of a family of antibiotics that work by interrupting the function of bacteria cells’ ribosomes , the complex molecular machines that create proteins by linking amino acids together.
What bacteria is streptomycin effective against?
Streptomycin has a broad spectrum of antibacterial activity. It is effective with respect to most Gram-negative and a few Gram-positive bacteria ; staphylococci, streptococci, pneumococci, gonococci, meningococci, stimulus of dysentery, brucellosis, tuberculosis, rabbit fever, plague, and others.
What does streptomycin kill?
Streptomycin kills bacteria by compromising the ribosome. • Streptomycin is an effective antibiotic because its structure is similar to that of the anticodons that would usually bind to the ribosome. • Streptomycin is significant because it was the first antibiotic that could treat tuberculosis.
What can streptomycin treat?
Streptomycin belongs to a class of drugs known as aminoglycoside antibiotics. It works by killing the organisms that cause the infection. This drug may also be used to treat other serious infections (e.g., Mycobacterium avium complex-MAC, tularemia, endocarditis, plague) along with other medications.
What is the most serious toxic effect of streptomycin?
Streptomycin injection is usually used for serious bacterial infections for which other medicines may not work. However, it may also cause some serious side effects, including damage to your hearing and sense of balance . These side effects may be more likely to occur in elderly patients and newborn infants.
Why is streptomycin not used?
A history of clinically significant hypersensitivity to streptomycin is a contraindication to its use. Clinically significant hypersensitivity to other aminoglycosides may contraindicate the use of streptomycin because of the known cross-sensitivity of patients to drugs in this class.
Is streptomycin still used today?
Streptomycin was discovered in 1943. It was the first antibiotic discovered that was effective against TB. Today it is widely used as a first line TB medicine in patients that have previously been treated for TB .
Why is streptomycin a good antibiotic?
Streptomycin is an aminoglycoside. It works by blocking the ability of 30S ribosomal subunits to make proteins , which results in bacterial death.
Is streptomycin a penicillin?
| Names | Other names Penicillin-streptomycin | Identifiers | CAS Number 8025-06-7 | 3D model (JSmol) Interactive image |
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Is bacteria sensitive to streptomycin?
Streptomycin, one of the few antibiotics used against plant pathogens, is active against aerobic Gram-negative bacteria .
Is streptomycin an antifungal?
| ChEBI Name streptomycin | ChEBI ID CHEBI:17076 |
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Is streptomycin an antibiotic?
Streptomycin is the first discovered aminoglycoside antibiotic , originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria.
Is streptomycin safe to use?
Streptomycin may cause nerve damage or hearing loss, especially if you have kidney disease or use certain other medicines. Tell your doctor right away if you have severe dizziness, hearing problems, vision problems, balance problems, trouble concentrating, muscle weakness, numbness, or tingling.
What is the effect of streptomycin?
SIDE EFFECTS: See also Warning section. Nausea, vomiting, stomach upset, or loss of appetite may occur . Pain/irritation/redness may occur at the injection site. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Which class of drugs does streptomycin belong to?
Streptomycin belongs to the class of medicines known as aminoglycoside antibiotics . It works by killing bacteria or preventing their growth.
