Eukaryotic microbial pathogens can
exhibit drug resistance through reducing the overall intracellular concentration of the drug
(less uptake, more efflux), by inactivating or failing to activate the drug, or by sequestering the drug away from its target.
Why is it harder to treat infections with eukaryotic pathogens?
Eukaryotic microbial pathogens can
exhibit drug resistance through reducing the overall intracellular concentration of the drug
(less uptake, more efflux), by inactivating or failing to activate the drug, or by sequestering the drug away from its target.
Why is it more challenging to develop drugs that target viruses and eukaryotic pathogens?
Because fungi, protozoans, and helminths are eukaryotic organisms like human cells, it is more challenging to develop antimicrobial drugs that specifically target them. Similarly, it is hard to target viruses because
human viruses replicate inside of human cells
.
Why do antibiotics work on prokaryotes and not eukaryotes?
b.
Antibiotics are simply
chemicals that kill prokaryotic cells but do not harm eukaryotic cells
. They are natural chemicals produced by fungi and bacteria that act to control their bacterial competitors. For example, streptomycin stops protein synthesis in prokaryotic cells by binding to their unusual ribosomes.
Are viruses more complex than eukaryotes?
Short story: Human cells are eukaryotic which means
they are more complicated
, bacteria cells are prokaryotic which means they are simpler and viruses are not even cells at all, they are just genetic material in a protein shell.
Can eukaryotes cause disease?
Many single-cell
eukaryotes can cause severe diseases to humans
. Human body is a rich source of nutrients which the parasites require for survival, as long as they can overcome the obstacles of human innate and adaptive immunity.
Are viruses eukaryotic?
Are viruses prokaryotic or eukaryotic?
Viruses are considered neither eukaryotes nor prokaryotes
. They are simpler than cells and lack the characteristics of living things. They are small protein particles and are only able to replicate inside of the cells they infect.
Viruses are tricky. They're small, mutate quickly, and make thousands and thousands of copies of themselves every day. Or rather, infected cells produce those new copies of the virus. Viruses
can't reproduce
on their own—they sit inert until they can infect a cell.
Aciclovir (or acyclovir) is an
antiviral medicine
. It treats infections caused by the herpes virus (herpes simplex), including: cold sores. genital herpes.
What germicides may lead to sterility?
High-level germicides
kill vegetative cells, fungi, viruses, and endospores, and can ultimately lead to sterilization.
Why do antibiotics not affect human cell translation?
Human cells do not make or need peptidoglycan
. Penicillin, one of the first antibiotics to be used widely, prevents the final cross-linking step, or transpeptidation, in assembly of this macromolecule. The result is a very fragile cell wall that bursts, killing the bacterium.
Why do antibiotics not work on viruses Bioninja?
Antibiotics block processes that occur in prokaryotic cells but not in eukaryotic cells.
Viruses lack a metabolism and cannot therefore be treated with antibiotics
.
Why do antibiotics not work against viruses biology?
Why don't antibiotics work on viruses? Viruses are different to bacteria; they have a different structure and a different way of surviving.
Viruses don't have cell walls that can be attacked by antibiotics
; instead they are surrounded by a protective protein coat.
Can viruses sense?
They do not respond to stimuli
, they do not grow, they do not do any of the things we normally associate with life. Strictly speaking, they should not be considered as “living” organisms at all.
Which cell is more complicated?
Eukaryotic cells
are more complex than prokaryotes, and the DNA is linear and found within a nucleus. Eukaryotic cells boast their own personal “power plants”, called mitochondria.
Are viruses made from cells?
Viruses are not cells
: they are not capable of self-replication and are not considered “alive”. Viruses do not have the ability to replicate their own genes, to synthesise all their proteins or to replicate on their own; thus, they need to parasitise the cells of other life-forms to do so.
